The effects of statins on blood pressure in normotensive or hypertensive subjects — A meta-analysis of randomized controlled trials
Statins are the lipid lowering treatment of choice for reducing cardiovascular (CV) risk among those with established cardiovascular disease (CVD) or at high risk of incident disease. They inhibit 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase which leads to a decrease in circulating total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) concentrations. Many studies have also investigated the potential role of statins in blood pressure (BP) among patients with hypertension; however, there is still a controversy over whether statin use results in a significant decrease in blood pressure (BP).
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